Picrorhiza (kutki) is found in the Himalayan mountains. It has been used in Ayurveda for centuries as a cure for jaundice, liver disease, indigestion and related digestive conditions.
Since the liver is responsible for among other things, cholesterol removal, any beneficial protective effect offered to liver cells will also result in an improved blood lipid profile.
Picroliv is a standardized mixture of iridoid glycosides containing 4% of the active agent, kutkin.
Kutkin, the active component is a mixture of picrosides and kutkosides.
Extracts of Pivrorhiza kurroa provide a hepato-protective ability to the body’s healing system The actual reason for that is glutathione stimulation and superoxide dismutase (SOD) activity.
The overall reactivity is improved through microsomal detoxification and free radical neutralization of the superoxide anion, thereby reducing the amount of lipid peroxidation products produced.
The accumulation of damaged products cause disease. Their reduction prevents it.
A reduction of triglycerides and cholesterol as well as inhibiting the inflammatory system is the purported benefits of picroliv. This occurs by minimizing the migration of white blood cells to areas of inflammation and stabilizing mast cells. The phytonutrients contained in Picroliv act via beta-adrenergic blockade, which accounts for its anti-inflammatory activity.
In addition to its role in inflammation, hepatoprotection, and antioxidant activity, extracts of Picrorhiza kurroa promotes the synthesis of nucleic acids and proteins, thereby promoting growth.